Factors influencing serum glycoprotein levels in the mouse and rat.

The changes in serum protein-bound hexose concentration following the injection of papain, hyaluronidase, estriol, ethylene and propylene glycol, Aminopterin, urethan, turpentine, adrenocorticotropin, and homogenates of normal and autolyzed liver have been examined. Neither stimulation nor suppression of cell proliferation had any marked effect on serum glycoproteins. Both normal and autolyzed liver were equally effective in producing a rise in serum glycoprotein levels. A rise occurred after sham op eration but not after partial hepatectomy.